Treating osteoporosis: do bisphosphonates really increase the risk of osteonecrosis of the jaw?

Osteoporosis is a major public health problem. Osteoporotic fractures result in significant morbidity, increased mortality and have a significant economic impact on healthcare systems. This is particularly true for hip fractures. Data from a study of hip fractures among Irish postmenopausal women showed a 23.6% mortality at 2 years compared to 10.1% among controls 1 . Hip fracture can lead to a reduction in independent mobility and living. The cost per hip fracture admission in Ireland has been estimated at €14,339 2 , which is in line with estimates from other European countries 3 These figures do not include additional indirect costs such as long-term residential care from loss of independence.